S-23: 15mg tablets. Each order contains 30 hard pressed tablets; tablets contain 15mg of S-23.
Inactive ingredients: Microcrystalline cellulose, magnesium stearate, Silica Di Oxide, Di-calicum Phosphate and USP grade food coloring.
All of our products are laboratory tested. We are working to make test results available to our customers. When labs are available you will be able to find them here. Link to lab
S-23 (SARM)
1. What It Does
S-23 is a non-steroidal selective androgen receptor modulator (SARM) originally developed by GTx, Inc., for potential use in male hormonal contraception and treatment of muscle wasting disorders. It binds to androgen receptors in a highly selective and potent manner, mimicking some of the effects of anabolic steroids but with more tissue selectivity.
S-23 works by:
Increasing anabolic activity in muscle and bone.
Suppressing endogenous testosterone production via hypothalamic-pituitary-gonadal (HPG) axis disruption.
Exhibiting a strong binding affinity to androgen receptors, stronger than many other SARMs.
Its high binding affinity and partial agonist activity in reproductive tissues differentiate it from weaker SARMs, making it one of the more potent agents under research.
2. Main Reported Benefits
Lean Muscle Gains: Noted for its ability to significantly increase lean muscle mass while reducing fat mass in animal studies.
Fat Loss: Many users report improved body composition due to simultaneous muscle gain and fat reduction.
Increased Strength: Anecdotal reports suggest enhanced power and performance during strength training.
Potential for Male Contraception: Suppresses luteinizing hormone (LH) and follicle-stimulating hormone (FSH), reducing sperm production.
Hardening and Drying Effect: Users often report a “dry” and vascular appearance, making it popular in cutting cycles.
3. Normal Applications
S-23 is strictly a research chemical and is not approved for medical use. Its primary experimental applications include:
Muscle Wasting Disorders: Evaluated for its ability to counteract muscle loss associated with chronic conditions or aging.
Male Hormonal Contraception: Studied for its ability to suppress spermatogenesis effectively without producing estrogenic side effects.
Body Recomposition: Popular in non-clinical, investigational uses focused on improving lean mass-to-fat ratios.
As with all SARMs, these applications are investigational and not approved by the FDA or similar agencies for human use outside clinical trials.
4. Common Side Effects
Because S-23 is one of the more potent SARMs, it may also carry a higher risk of side effects, especially when misused:
Testosterone Suppression: Strong suppression of natural testosterone production, requiring post-cycle therapy (PCT).
Aggression or Mood Swings: Some users report irritability or changes in mood.
Shrinkage of Testicles (in animal studies): Related to suppressed gonadotropin levels.
Night Sweats or Hot Flashes: Likely due to hormonal fluctuations.
Hair Shedding: Reported in sensitive individuals due to strong androgen activity.
Long-term safety data in humans is lacking. Most findings come from animal studies or anecdotal user experiences.
5. Recommended Administration or Dosage
Disclaimer: The following dosing information is based on anecdotal reports from research communities. S-23 is not approved for human use, and no clinically verified dosing guidelines exist.
Dosage Range: 10–30 mg per day.
Administration: Orally, once or twice daily (due to ~12-hour half-life).
Cycle Length: 6–8 weeks is common among research subjects.
PCT Requirement: A full post-cycle therapy with SERMs (e.g., Nolvadex or Clomid) is strongly advised due to its suppressive nature.
Half-Life: Estimated between 10–12 hours, requiring split dosing for stable plasma levels.
Due to its strong suppressive effects, many researchers recommend avoiding stacking S-23 with other suppressive compounds unless specifically studying synergistic effects.
